Nucleoside 5′-O-Triphosphates are usually substates or inhibitors of polymerases. They are widely used in drug Discovery for a varies of viruses like HCV, HBV, HIV, and Coronavirus to target either RNA dependent RNA polymerases, DNA dependent DNA polymerases, reverse transcribe DNA polymerases. We are also able to synthesize 5′-O-tetraphosphate, 5′-O-pentaphosphate, 5′-O-hexaphosphate, 5′-O-nonaphosphate, and 5′-O-polyphosphate nucleotide analogues. We are also working on oligonucleotides, and conjugation of oligonucleotides with lipid and fluorescence dye.
