Nucleoside 5′-O-Triphosphates are usually substates or inhibitors of polymerases. They are widely used in drug Discovery for a varies of viruses like HCV, HBV, HIV, and Coronavirus to target either RNA dependent RNA polymerases, DNA dependent DNA polymerases, reverse transcribe DNA polymerases. We are also able to synthesize 5′-O-tetraphosphate, 5′-O-pentaphosphate, 5′-O-hexaphosphate, 5′-O-nonaphosphate, and 5′-O-polyphosphate nucleotide analogues. We are also working on oligonucleotides, and conjugation of oligonucleotides with lipid and fluorescence dye.
Biotin-11-ddUTP
Biotin-11-ddCTP
Biotin-11-ddATP
Biotin-11-ddGTP
Biotin-11-dUTP
Biotin-11-dCTP
Biotin-11-dATP
Biotin-11-dGTP
5-Biotin-UTPBiotin-11-CTP
Biotin-11-ATP
Biotin-11-GTP
Coumarin-11-ddUTP
Coumarin-11-ddCTP
Coumarin-11-ddATP
Coumarin-11-ddGTP
Coumarin-11-dUTP
Coumarin-11-dCTP
Coumarin-11-dATP
Coumarin-11-dGTP
Figure 1. Chemical Modified Nucleoside 5′-O-Triphosphates Analogues
Figure 2. Chemical Modified Nucleoside 5′-O-Triphosphate Analogues
Figure 3. Chemical Modified Nucleoside 5′-O-Triphosphate Analogues
Figure 4. Chemical Modified Nucleoside 5′-O-Triphosphate Analogues
